49ers Vs. Seahawks Picks: Our Best Bets For Thursday Night Football

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49ers Vs. Seahawks Picks: Our Best Bets For Thursday Night Football

Our team of experts dive into the NFL action, focusing on insights and odds from top betting sites as San Francisco face Seattle on Thursday night.

Continue reading for The Panel's in-depth coverage and expert predictions as the NFL season continues.

49ers Vs. Seahawks Pick: San Francisco Need The Win

The 49ers and Seahawks are expected to be better off in the NFC West, but last week's rough losses put both of them in a predicament. 

San Francisco rank 4th in red zone possessions but 30th in touchdown conversions. Look at last week versus Arizona. They scored two touchdowns but had to settle for three field goals. 

Add in three turnovers, and Arizona was able to steal a win from last year’s NFC Champion. San Francisco have an opportunity versus a Seattle team that has looked ordinary the past two weeks. 

If San Francisco can learn from the New York Giants' performance last week, the 49ers should return to .500 this week and cover the 3.5 points they are laying.

The Panel Pick 1: San Francisco -3.5 Points | DraftKings -105

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49ers Vs. Seahawks Prediction: What A Passing Fancy

Brock Purdy needs to create additional yards sometimes. However, he has gone over 280 yards three times this season.

It is hard to believe that San Francisco are 2-3, but here we are. Again, a few points here and there, and this team could be 5-0. 

Their three losses have come by a combined 10 points. That is due to Purdy's and maybe Jordan Mason's lack of execution in critical situations.

San Francisco's chances of getting over 25.5 Points are high, too. That rolls in at -120 with betting apps

So, the next Panel pick for this Thursday night is for Brock Purdy to get at least 248 passing yards.

The Panel Pick 2: Brock Purdy Over 247.5 Yards | -115 With BetMGM

49ers Vs Seahawks Preview: Off To The Races

San Francisco has scored 30+ points twice this year, and honestly, that number should be four or five.

Seattle can score, too. We saw that on a Monday night in Detroit, where 29 points was nowhere near close to enough and they have yet to top 30 this season.

Since Caesars does not offer a Race To 30 option, we will settle for the 25 and side with San Francisco. They have the potential to easily become a Top 5 offense. San Francisco was sixth in 2022 and third in 2023. 

The Panel pick is for San Francisco to hit the 25 point mark first on Thursday night.

The Panel Pick 3: San Francisco The First To 25 Points | -120 With Caesars

* While you're here, why not check out more NFL picks from the our other experts on The Panel: